Spiramycin: UseS DoseS, Side effects, Prevention & Warnings, Interaction, Overdose

What is Spiramycin for?

Spiramycin is a drug with a function to treat various kinds of infections. Often used to treat toxoplasmosis in pregnant women because this drug reduces the chance of infection in the baby. This medicine can also be used for other problems as directed by your doctor. Cannot be used to treat fever, flu, or other viral infections.

Spiramycin dosage and side effects of spiramycin will be explained further below.

How to use Spiramycin?

Spiramycin is best used before eating.

To completely eliminate the infection, continue using it during the treatment period, even if you feel better after a few days of treatment. If you stop using it too soon, symptoms can return.

This drug works best when there are constant drug levels in the blood. To keep it constant, don’t forget about the dose. For best results use at the same time during the day and night. If this affects your sleep time and other activities, or if you need planning to determine the time to use the drug, discuss it with your health care provider.

For patients using Spiramycin suppository:

  • Open the wrapper and wet the suppository with cold water. Lie on one side and use your fingers to push the suppository into the rectum

How is Spiramycin stored?

This drug is best stored at room temperature, away from direct light and damp places. Do not store in the bathroom. Don’t freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product packaging or ask your pharmacist. Keep all medicines out of the reach of children and pets.

Do not flush medicine in the toilet or in the sewer unless instructed. Discard this product when it has expired or if it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.


The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the dose of Spiramycin for adults?

Oral dose in adults (capsules or tablets):

Adults and teenagers – 1-2 grams (3,000,000-6,000,000 International Units [IU]) twice a day, or 500 mg-1 gram (1,500,000-3,000,000 IU) three times a day. For severe infections, the dose is 2-2.5 grams (6,000,000-7,500,000 IU) twice a day.

Injection dose in adults:

Adults and teens – 500 mg (1,500,000) is injected slowly into the pulse every eight hours. For severe infections, a dose of 1 gram (3,000,000 IU) is slowly injected into the pulse every eight hours.

Rectal dose in adults:

Adults and children aged 12 years and over — two or three 750 mg (1,950,000 IU) per day.

Children up to the age of 12 years – two or three 500 mg (1,300,000 IU) suppository per day.

What is the dose of Spiramycin for children?

Oral dose in children (capsules or tablets):

Children weighing 20 kg (44 pounds) or more — Dose based on body weight. The usual dose is 25 mg (75,000 IU) per kg (11.4 mg per pound) body weight twice a day, or 17 mg (51,000 IU) per kg (7.7 mg per pound) body weight three times a day.

Injection dose of children:

Children — use and dosage must be with the doctor’s approval.

Rectal doses in children (suppository):

Children up to age 12 years – two or three 500 mg (1,300,000 IU) suppository per day.

Newborns — dosage based on body weight. The usual dose is one 250 mg (650,000 IU) per 5 kg (250 mg suppository per 11 pounds) body weight once a day.

In what dosages is Spiramycin available?





Side effects

What side effects can be experienced due to Spiramycin?

Digestive problems, nausea, vomiting, diarrhea, or stomach pain can occur. If these symptoms continue or are increasingly disturbing, contact your doctor. If you experience an allergic reaction to this medicine, seek medical help immediately. Symptoms of an allergic reaction can include: itching, difficulty breathing, swelling of the face, lips, tongue, or throat.

Not everyone experiences the above side effects. There may be some side effects not mentioned above. If you have concerns about certain side effects, consult your doctor or pharmacist.

Prevention & Warnings

What should be known before using Spiramycin?

Liver disorders; pregnancy and breastfeeding. Pay attention to the function of the heart. History of arrhythmia or tendency or prolongation of the QT interval.

Is Spiramycin safe for pregnant and lactating women?

There is no adequate research on the risk of using this drug in pregnant or nursing women. Always consult your doctor to consider the potential benefits and risks before using this medicine. This drug is included in the category C pregnancy risk according to the US Food and Drugs Administration (FDA)

The following are references to pregnancy risk categories according to the FDA:

  • A = No risk
  • B = No risk in several studies
  • C = Maybe risky
  • D = There is positive evidence of risk
  • X = Contraindications

· N = Unknown


What medicines might interact with Spiramycin?

Although certain drugs are not recommended for use together, in other cases two different drugs can be used together although drug interactions may occur. In cases like this, your doctor may change the dosage, or other precautions that need to be taken. Notify your health care provider if you use other prescription or non-prescription drugs.

Increased risk of ventricular arrhythmias when concomitant with astemizole, cisapride, and terbenadine. Risk of acute dystonia when concomitant use with fluphenazine.

Can food or alcohol interact with Spiramycin?

Certain medicines should not be used when eating or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions can interact with Spiramycin?

Other health problems can affect the use of this drug. Tell your doctor if you have other health problems.


What should I do in an emergency or overdose?

In cases of emergency or overdose, contact the local emergency services provider (112) or immediately to the nearest hospital emergency department.

What should I do if I miss a dose?

If you forget one dose of this medicine, take it as soon as possible. But when it is nearing the next dose, skip the missed dose and return to the usual dosage schedule. Do not double the dose.


Please enter your comment!
Please enter your name here