Aceclofenac: Uses, Dosage, Side Effects, Prevention & Warnings, Price, Composition

Functions & Uses

What is the drug Aceclofenac used for?

Aceclofenac is a medicine to reduce pain and inflammation in patients suffering from arthritis (osteoporosis), an autoimmune disease that causes inflammation of the joints (rheumatoid arthritis) and arthritis of the spine (ankylosing spondylitis).

Aceclofenac belongs to a group of drugs called non-steroidal anti-inflammatory drugs (NSAIDs). This medicine has anti-inflammatory and painkillers.

Aceclofenac works by blocking the production of substances called prostaglandins. Prostaglandins are released in the injured part, damaged tissue and immune reaction. Prostaglandins play an important role both in the body’s inflammatory response and stimulating bone re-absorption in disease.

What are the rules for using Aceclofenac?

Always take this medication exactly as instructed by your doctor or pharmacist. You will be prescribed the lowest effective dose for the shortest duration to reduce side effects. Consult your doctor or pharmacist if you feel unsure.

The recommended dose for adults is 200 mg (two Aceclofenac tablets). One 100 mg tablet should be taken in the morning and one at night.

The tablets must be swallowed whole with plenty of water and must be taken with or after meals. Do not crush or chew the tablet.

Do not exceed the prescribed daily dose.

How do you save Aceclofenac?

Store at room temperature, keep away from direct light and a humid place. Do not store in the bathroom. Don’t freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product packaging or ask your pharmacist. Keep all medicines out of the reach of children and pets.

Do not flush medicine in the toilet or in the sewer unless instructed. Discard this product when it has expired or if it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.

Prevention & Warnings

What should be considered before using the drug Aceclofenac?

Before you start taking Aceclofenac, tell your doctor:

  • If you suffer from kidney or liver disease and the like
  • If you have the following disorders, it can worsen the condition:
  1. Digestive disorders in the upper or lower canal
  2. Inflammatory bowel disease (Ulcerative Colitis)
  3. Chrohn’s diseases
  4. Ulceration, bleeding or perforation
  5. Blood disorders
  • If you experience or have experienced problems with blood circulation to your brain
  • If you suffer from asthma or other respiratory problems
  • When you suffer from porphyria
  • If you have heart problems, have had a stroke before or you might be at risk from this condition (for example, if you have high blood pressure, diabetes, high cholesterol or an active smoker)

You should discuss your treatment first with your doctor or pharmacist.

  • If you have chicken pox, you should avoid using this medicine because it is a rare serious infection of the skin associated with this use
  • If you have just recovered from a major operation.
  • If you are an elderly person, your doctor will prescribe the lowest effective dose of medication.

Hypersensitivity reactions can occur and very rarely, very serious allergic reactions will occur (see section 4. Possible side effects). This risk is higher in the first month of treatment. Aceclofenac must be stopped at the beginning of the first skin rash, mucous membrane injury or signs of hypersensitivity.

Medications such as Aceclofenac may be associated with a small increased risk of heart attack (“myocardial infarction”) or stroke. The risk is more likely to increase with high doses and long-term treatment. Do not exceed the recommended dose or duration of treatment.

Do not use Aceclofenac:

  • If you are allergic to aceclofenac or one of the other ingredients of this drug (listed in section 6)
  • If you are allergic to aspirin or other NSAIDs (for example ibuprofen, naproxen or diclofenac).
  • If you take other NSAID aspirin and then experience one of the following:
  1. Asthma attack
  2. Colds, itching, and / or sneezing (nasal irritation)
  3. The skin has a reddish rash, itching sting and even feels like burning
  4. Severe allergic reaction (anaphylactic shock). Symptoms include difficulty breathing, wheezing, abnormal pain and vomiting.
  • If you have a history of gastric injury or intestinal bleeding
  • If you suffer from severe kidney disease
  • If you have or have had severe heart failure (heart attack)
  • If you have or are suspected of suffering from severe liver failure
  • If you suffer from bleeding or bleeding disorders
  • If you are pregnant (unless the drug is recommended by your doctor)

Is the drug Aceclofenac safe for pregnant and nursing women?

There is no adequate research on the risks of using this drug in pregnant or nursing women. Always consult your doctor to consider the potential benefits and risks before using this medicine. This drug is included in the risk of pregnancy category C.

  • A = No risk
  • B = No risk in several studies
  • C = Maybe risky
  • D = There is positive evidence of risk
  • X = Contraindications
  • N = Unknown

Side effects

What side effects might Aceclofenac have?

Like all medicines, Aceclofenac can cause side effects, although not everyone gets these side effects.

If you experience any of the following side effects, then immediately inform your doctor:

  • Medications such as Aceclofenac may be associated with a small increased risk of heart attack, myocardial infarction, or stroke
  • Severe allergic reactions (anaphylactic shock). Symptoms may include difficulty breathing, wheezing, abnormal pain and vomiting.
  • Facial swelling
  • Kidney failure

If you experience side effects like the following during your treatment period, STOP USE of the drug and seek medical help immediately:

  • Throw away the bleeding
  • Black stool
  • Vomiting blood or in the vomit there are black particles such as coffee grounds

STOP USING drugs and notify your doctor if you experience:

  • Indigestion or heartburn
  • Abdominal pain (pain in your stomach) or other abnormal stomach symptoms

Not everyone experiences the following side effects. There may be some side effects not mentioned above. If you have concerns about certain side effects, consult your doctor or pharmacist.

Drug Interactions

What medicines can interfere with the work of Aceclofenac?

Although some drugs may not be taken together at all, in other cases some drugs can also be used together although interactions may occur. In cases like this, the doctor may change the dose, or do other prevention things that are needed. Let your doctor know if you are taking other drugs both over the counter and from a prescription.

Tell your doctor if you consume:

  • Medications used to treat depression (selective serotonin-reuptake inhibitors) or manic depression (lithium)
  • Medications used to treat heart failure and irregular heartbeats (cardiac glycosides such as digoxin)
  • Medications used to treat high blood pressure (antihypertension)
  • Quinolone antibiotics
  • Medications used to increase the rate of excretion of urine (diuretics)
  • Drugs that stop blood clots (anticoagulants) such as warfarin, heparin
  • Methotrexate which is used to treat cancer and autoimmune disorders
  • Mifepristone
  • Steroid (estrogen, androgen, atau glucocorticoids)
  • Medications used to suppress the immune system (cyclosporin or tacrolimus)
  • Medications used to treat HIV (AZT)
  • Medications used to reduce blood sugar levels (antidiabetics)
  • Obat NSAID lainnya (aspirin, ibuprofen, naproxen), including COX-2 inhibitors)

Can certain foods and drinks interfere with the action of Aceclofenac?

Certain medicines should not be used when eating or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions can interfere with the performance of the drug Aceclofenac?

Other health conditions that you have can affect the use of this drug. Always tell your doctor if you have other health problems.


The information provided is not a substitute for a doctor’s prescription. ALWAYS consult a doctor or pharmacist before starting treatment.

What is the dose of the drug Aceclofenac for adults?

The recommended dose is 200 mg a day, taken separately 100 mg per dose, one tablet in the morning and one at night.

What is the dose of the drug Aceclofenac for children?

Safety and effectiveness have not been determined in pediatric patients (less than 18 years).

In what dosages and preparations is Aceclofenac available?

Tablet, oral: 100 mg

What should be done in an emergency or overdose?

In cases of emergency or overdose, contact your local emergency services provider (119) or immediately to the nearest hospital emergency department.

Symptoms of an overdose may include:

  • Headache
  • Nausea
  • Gag
  • Epigastric pain
  • Gastrointestinal irritation
  • Gastrointestinal bleeding
  • Rare diarrhea
  • Disorientation
  • Excitation
  • Arriving
  • Sleepy
  • Dizzy
  • Tinnitus
  • Hypotension
  • Respiratory depression
  • Passed out
  • Occasional spasms

In cases of significant poisoning, acute kidney failure and liver damage may occur.

What to do if you forget to take medication or forget to take medicine?

If you forget one dose of this medicine, take it as soon as possible. But when it is nearing the next dose, skip the missed dose and return to the usual dosage schedule. Do not double the dose.


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